Inotek's Adenosine Publications

2004

Jagtap P, Chen Z, Szabó C, Klotz K. 2004.   2-(N-Acyl) and 2-N-acyl-N6-substituted analogues of adenosine and their affinity at the human adenosine receptors.  Bioorganic & Medicinal Chemistry Letters 14:1495-1498

2003

Mabley JG, Soriano FG, Pacher P, Haskó G, Marton A, Wallace R, Salzman AL, Szabó C. 2003. The adenosine A3 receptor agonist N6-(3-iodobenzyl)-adenosine-5’-N-methyluronamide, reduces inflammation and oxidative damage in two murine models of colitis.  Eur J Pharmacol, 466:323-329.

Németh Z, Leibovich J, Deitch EA, Vizi SE, Szabó C, Haskó G. 2003. cDNA microarray analysis reveals a NF-kB- independent regulation of macrophage function by adenosine. J Pharmacol Exp Ther 306: 1042-1049.

Németh Z, Leibovich S, Deitch E, Sperlagh B, Virag L, Vizi E, Szabó C, Haskó G. 2003. Adenosine stimulates CREB activation in macrophages via a p38 MAPK-mediatd mechanism. Biochemical & Biophysical Research Communications 312: 883-888.

Pinhal-Enfield G, Ramanathan M, Haskó G, Vogel SN, Salzman AL, Boons GJ, Leibovich SJ. 2003. An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors. Am J Pathol 163:711-21.

2002

Haskó G, Deitch EA, Szabó C, Németh ZH, Vizi ES. 2002. Adenosine: a potential mediator of immunosuppression in multiple organ failure.  Current Opinion in Pharmacology 2:440-444.

1999

Haskó G, Kuhel DG, Chen JF, Schwarzschild MA, Deitch EA, Mabley JG, Marton A, Szabó C. 1999. Adenosine inhibits IL-12 and TNF-a production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J 14:2065-74.

Haskó G, Németh ZH, Salzman AL, Vizi ES, Szabó C. 1999. An agonist of A3 adenosine receptors decreases IL-12, IFN and nitric oxide production and prevents lethality in endotoxemic mice. Eur J Pharmacol 358:261-268.

1998

Szabó C, Scott GS, Virág L, Egnaczyk G, Salzman AL, Shanley TP, Haskó G. 1998. Suppression of macrophage inflammatory protein (MIP)-1 alpha production and collagen-induced arthritis by adenosine receptor agonists. Br J Pharmacol 125:379-387.

1996

Haskó G, Szabó C, Németh ZH, Kvetan V, Pastores SM, Vizi ES. 1996. Adenosine receptor agonists differentially regulate IL-10 and TNF production in endotoxemic mice. J Immunol 157:4634-4640.