Inotek Publications

Parikh AA, Moon MR, Pritts TA, Fischer JE, Szabó C, Hasselgren PO, Salzman AL. 2000. IL-1beta induction of NF-κB activation in human intestinal epithelial cells is independent of oxyradical signaling. Shock 13:8-13.

Haskó G, Kuhel DG, Salzman AL, Szabó C. 2000. ATP suppression of interleukin-12 and tumour necrosis factor-alpha release from macrophages. Br J Pharmacol 129:909-914. 913 kb PDF

Moon MR, Parikh AA, Pritts TA, Kane C, Fischer JE, Salzman AL, Hasselgren PO. 2000. Interleukin-1beta induces complement component C3 and IL-6 production at the basolateral and apical membranes in a human intestinal epithelial cell line. Shock. 13:374-8.

Pritts TA, Moon MR, Wang Q, Hungness ES, Salzman AL, Fischer JE, Hasselgren PO. 2000. Activation of NF-kappaB varies in different regions of the gastrointestinal tract during endotoxemia. Shock. 14:118-22.

Haskó G, Kuhel DG, Németh ZH, Mabley JG, Stachlewitz RF, Virág L, Lohinai Z, Southan GJ, Salzman AL, Szabó C. 2000. Inosine inhibits inflammatory cytokine production by a post-transcriptional mechanism and protects against endotoxic shock. J Immunol 164:1013-9. 816 kb PDF

Kiroycheva M, Ahmed F, Anthony GM, Szabó C, Southan GJ, Bank N. 2000. MAP kinase phosphorylation in kidneys of sickle cell mice. J Am Soc Nephrol 11:1026-1032. 1.76 MB PDF

Soejima K, McGuire R, Snyder N, Uchida T, Szabó C, Salzman AL, Traber LD, Traber DL. 2000. The effect of inducible nitric oxide synthase inhibition on smoke inhalation injury in sheep. Shock 13:261-6. 1.05 MB PDF

Szabó C. 2000. Anti-peroxynitrite strategies for the experimental therapy of shock. Crit Care Med 28:2156-7.

Haskó G, Kuhel DG, Marton A, Nemeth ZH, Deitch EA, Szabó C. 2000. Spermine differentially regulates the production of interleukin-12 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma. Shock 14:144-149.

Liaudet L, Szabó A, Soriano FG, Zingarelli B, Szabó C, Salzman AL. 2000. Poly (ADP-ribose) synthetase activation mediates intestinal mucosal barrier dysfunction after mesenteric ischemia. Shock 14:134-141. 1.54 MB PDF

Bank N, Kiroycheva M, Singhal PC, Anthony GM, Southan GJ, Szabó C. 2000. Inhibition of nitric oxide synthase ameliorates cellular injury in sickle cell mouse kidneys. Kidney Int 58:82-89. 3.63 MB PDF

Bernstein T, Szabó C, Salzman AL. 2000. Maturation-dependent sequential expression of interferon regulatory factor-1 and inducible nitric oxide synthase in cultured human enterocytes. Shock 14:514-21.

Liaudet L, Soriano FG, Szabó E, Virág L, Mabley JG, Salzman AL, Szabó C. 2000. Protection against hemorrhagic shock in mice genetically deficient in poly (ADP-ribose) polymerase. Proc Natl Acad Sci USA 97:10203-10208. 218 kb PDF

Szabó C. 2000. Role of nitric oxide in inflammation. In: Nitric Oxide - Biology and Pathobiology (L. Ignarro, Ed). Academic Press, New York, 841-872. 7.39 MB PDF

Cell death: the role of PARP (Szabó C, Ed.), CRC Press, Boca Raton, Florida, 2000.

Szabó C. 2000. Activation of poly (ADP-ribose) synthetase in the pathogenesis of ischemia-reperfusion injury. In: From DNA damage and stress signaling to cell death; poly ADP-ribosylation reactions (G. De Murcia, S. Shall, Eds). Oxford University Press, 151-176.

Vincent JL, Zhang H, Szabó C, Preiser JC. 2000. Effects of nitric oxide in septic shock. Am J Resp Crit Care Med 161:1781-1785. 1.08 MB PDF

Whalen MJ, Clark RSB, Dixon CE, Robichaud P, Marion DW, Vagni V, Graham S, Virág L, Haskó G, Stachlewitz RF, Szabó C, Kochanek P. 2000. Traumatic brain injury in mice deficient in poly (ADP-ribose) polymerase: a preliminary report. Acta Neurochir [Suppl] 76:61-64.

Lorch SA, Foust R 3rd, Gow A, Arkovitz M, Salzman AL, Szabó C, Vayert B, Geffard M, Ischiropoulos H. 2000. Immunohistochemical localization of protein 3-nitrotyrosine and S-nitrosocysteine in a murine model of inhaled nitric oxide therapy. Pediatr Res 47:798-805. 13 MB PDF

Salzman AL, Preiser JC, Setchell K, Szabó C. 2000. Isoflavone-mediated inhibition of tyrosine kinase: a novel anti-inflammatory approach. J Medicinal Food 2:179-181.

Liaudet L, Soriano FG, Szabó C. 2000. Biology of nitric oxide signaling. Crit Care Med 28 (Suppl):N37-N52.

Szabó C, Snyder SS. 2000. Introduction: Cell death by energy depletion: a re-emerging concept via the nitric oxide connection. In: Cell death: the role of PARP (Szabó C, Ed), CRC Press, Boca Raton, Florida, 1-6.

Szabó C. 2000. Role of PARP activation in the pathophysiology of circulatory shock. In: Cell death: the role of PARP (Szabó C, Ed), CRC Press, Boca Raton, Florida, 81-102.

Wilmott RW, Kitzmiller JA, Szabó C, Southan GJ, Salzman AL. 2000. Mercapto-ethylguanidinine reduces the inflammatory response in a murine model of chronic infection with pseudomonas aeruginosa. J Pharmacol Exp Ther 292:88-95 1.2 MB PDF

Virág L, Szabó C. 2000. Bcl-2 protects peroxynitrite-treated thymocytes from poly (ADP-ribose) synthase (PARS) independent apoptotic but not from PARS-mediated necrotic cell death. Free Rad Biol Med 29:704-713. 1.22 MB PDF

Salzman AL, Denenberg A, Linn SC, Szabó C. 2000. Progesterone inhibits inducible nitric oxide synthase mRNA expression in human epithelial cells Int J Mol Med 6:209-216. 1.22 MB PDF

Wolfard A, Kaszaki J, Szabó C, Szalay L, Nagy S, Boros M. 2000. Prevention of early myocardial depression in hyperdynamic endotoxemia in dogs. Shock 13:46-51.

Yang Z, Zingarelli B, Szabó C. 2000. Role of poly (ADP-ribose) synthetase in the delayed myocardial ischemia-reperfusion injury. Shock 13:60-66. 2.55 MB PDF

Yang Z, Zingarelli B, Szabó C. 2000. The crucial role of endogenous interleukin-10 production in myocardial ischemia-reperfusion injury. Circulation, 101:1019-1026. 409 kb PDF